When Will Grey'S Anatomy Return In 2025 Season. Despite shakeups in the cast across seasons 19 and 20, the. Season 21 premieres thursday, september 26, 2025 on abc.
Here’s why, what will air instead on abc and when season 21, episode 9 returns. The new season of grey’s anatomy premiered on abc on march 14, 2025 at 8 p.m.